Selected literature

Soft tissue management

Our collagen sponges promote wound healing with their highly hemostatic effect and the soft tissue graft mucoderm is a true alternative in certain indications to the patient’s own connective tissue. Straumann® Emdogain®, a biologic product, contains a mix of proteins designed to accelerate soft tissue wound healing after oral surgical procedures.    

botiss mucoderm® provides a true alternative in certain indications to the patient’s own connective tissue. This stable 3-dimensional collagen soft tissue replacement, made of porcine dermis, supports fast revascularization and soft tissue integration, including color and texture. The mucoderm® has been successfully used in more than 20.000 treatments.

The Use of a Novel Porcine Derived Acellular Dermal Matrix (mucoderm®) in Peri-Implant Soft Tissue Augmentation: Preliminary Results of a Prospective Pilot Cohort Study. Papi P. and Pompa G. BioMed Research International 2018.

Treatment of multiple maxillary adjacent class I and II gingival recessions with modified coronally advanced tunnel and a new xenogeneic acellular dermal matrix. Vincent-Bugnas S. et al. J Esthet Restor Dent. 2018 Mar;30(2):89-95.Epub. 2017.

Changes of the peri-implant soft tissue thickness after grafting with a collagen matrix. Zafiropoulos GG. et al. J Indian Soc Periodontol. 2016;20(4):441-445.

Clinical evaluation of a porcine acellular dermal matrix for the treatment of multiple adjacent class I, II, and III gingival recessions using the modified coronally advanced tunnel technique. Cosgarea R, Juncar R, Arweiler N, Lascu L, Sculean A. Quintessence Int. 2016; 47(9):739-47.

Vertical soft tissue augmentation with porcine-derived collagen matrix membrane. A prospective study with 20 consecutive patients. Puisys A, Schlee M, Vindasiute E, Linkevicius T. Data presented during the 2th congress of the European Association of Osseointegration, Stockholm, Sweden, September 24th – 26th 2015. 

Presentation of a modified method of vestibuloplasty with an early prosthetic loading. Konstantinova D, Djongova E, Arnautska H, Georgiev T, Peev S, Dimova M. J of IMAB. 2015; 21(4):964-968.

Biofunctionalization of porcine-derived collagen matrix using enamel matrix derivative and platelet-rich fibrin: influence on mature endothelial cell characteristics in vitro. Park JS, Pabst AM, Ackermann M, Moergel M, Jung J, Kasaj A.  Clin Oral Investig. 2018; 22(2):909-917. Epub 2017.

Soft tissue volume alterations after connective tissue grafting at teeth: the subepithelial autologous connective tissue graft versus a porcine collagen matrix - a pre-clinical volumetric analysis. Schmitt CM, Matta RE, Moest T, Humann J, Gammel L, Neukam FW, Schlegel KA. J Clin Periodontol. 2016; 43(7):609-17.

The influence of various rehydration protocols on biomechanical properties of different acellular tissue matrices. Kasaj A, Levin L, Stratul SL, Götz H, Schlee M, Rütters CB, Konerding MA, Ackermann M, Willershausen B, Pabst AM. Clin Oral Invest. 2016; 20(6):1303-15. Epub 2015.

Biodegradation pattern and tissue integration of native and cross-linked porcine collagen soft tissue augmentation matrices – an experimental study in the rat. Rothamel D, Benner M, Fienitz T, Happe A, Kreppel M, Nickenig JH and Zöller JE. Head and Face 2014, 10:10. 

In vitro and in vivo characterization of porcine acellular dermal matrix for gingival augmentation procedures. Pabst AM, Happe A, Callaway A, Ziebart T, Stratul SI, Ackermann M, Konerding MA, Willershausen B, Kasaj A.  J Periodont Res 2014; 49(3):371-81. Epub 2013.

The influence of various rehydration protocols on biomechanical properties of different acellular tissue matrices. Kasaj A, Levin L, Stratul SI, Götz H, Schlee M, Rütters CB, Konerding MA, Ackermann M, Willershausen B, Pabst AM. Clin Oral Investig. 2016 Jul;20(6):1303-15.

Healing of localized gingival recessions treated with a coronally advanced flap alone or combined with an enamel matrix derivative and a porcine acellular dermal matrix: a preclinical study. Shirakata Y, Sculean A, Shinohara Y, Sena K, Takeuchi N, Bosshardt DD, Noguchi K.  Clin Oral Investig. 2016 Sep;20(7):1791-800.

Tunnel Technique With Collagen Matrix Compared With Connective Tissue Graft for Treatment of Periodontal Recession: A Randomized Clinical Trial. Cieślik-Wegemund M, Wierucka-Młynarczyk B, Tanasiewicz M, Gilowski Ł. J Periodontol. 2016 Dec;87(12):1436-1443. Epub 2016 Jul 17. 

Evaluation of a porcine collagen matrix to create new keratinized tissue at deficient implant sites: 12 months results from a controlled prospective clinical study. Stricker A, Rothamel D, Stübinger S, Fleiner J. Clin. Oral Impl. Res. 25 (Suppl. 10), 2014 (poster).

The influence of mucosal tissue thickening on crestal bone stability around bone-level implants. A prospective controlled clinical trial. Puisys A, Linkevicius T. Clin Oral Implants Res. 2015 Feb;26(2):123-9. 

No guarantee of completeness.

botiss Jason® fleece and botiss collacone® are both native collagen sponges with a highly efficient local hemostatic effect. They stabilizing the coagulum and minimizes the risk of secondary bleeding.

Pre-clinical

Impact of matrix compactness on tissue integration, blood vessel invasion and biodegradation of porcine collagen matrices – an experimental study in the rat. Fienitz T, Rothamel D, Barth Y, Neugebauer J, Kreppel M, Happe A, Zöller J Clin Oral Impl. Res 25(10). 2014. Poster 228. 

Effects of EMD-liquid (Osteogain) on periodontal healing in class III furcation defects in monkeys. Shirakata Y, Miron R.J, Nakamura T, Sena K, Shinohara Y, Horai N, Bosshardt D.D, Noguchi K, Sculean A. J Clin Periodontol. 2017; 44(3):298-307.

Absorbable collagen sponges loaded with recombinant bone morphogenetic protein 9 induces greater osteoblast differentiation when compared to bone morphogenetic protein 2. Fujioka‐Kobayashi M, Schaller B, Saulacic N, Pippenger BE, Zhang Y, Miron RJ. Clin Exp Dent Res. 2017; 3:32–40.

Healing of two-wall intra-bony defects treated with a novel EMD-liquid-A pre-clinical study in monkeys. Shirakata Y, Miron RJ, Shinohara Y, Nakamura T, Sena K, Horai N, Bosshardt DD, Noguchi K, Sculean A. J Clin Periodontol. 2017; 44(12):1264-1273.

Clinical

Efficacy and Biocompatibility of Jason® Collagen Fleece for Haemostasis after Iliac Crest Harvesting of Autologous Cancellous Bone – An Observationional Clinical Study. Fleege C., Schmidt J., Schmidt I., Zukowski D. and Rauschmann M European Musculoskeletal Review 7(4):240-242 January 2012. 

Prevention of post-operative bleeding in hemostatic compromised patients using native porcine collagen fleeces-retrospective study of a consecutive case series.  Zirk M et al. Oral Maxillofac Surg. 2016;20(3):249-54. 

Diode laser for harvesting de-epithelialized palatal graft in the treatment of gingival recession defects: A randomized clinical trial.Ozcelik O, Seydaoglu G, Haytac CM. J Clin Periodontol. 2016; 43(1):63-71.

Alveolar Ridge Preservation Using a Novel Synthetic Grafting Material: A Case with Two-Year Follow-Up. Fairbairn P, Leventis M, Mangham C, Horowitz R. Case Rep Dent. 2018; 2018:6412806. 

No guarantee of completeness.